Antimüllerian Hormone as a Predictor of Natural Fecundability in Women Aged 30–42 Years
This small study is valuable because it tracked normal women who were beginning their efforts to conceive. So many studies that are retrospective, leave out the women who fail and are therefore not identified.
The study included only 100 women, therefore they had to divide the data into dichotomous (single cut-off point) values whereas we recognize that the measurements are actually continuous with more varied implications.
[box type=”info”]AMH appears to be a predictor of age-related decline in female fertility. The data suggests that these markers apply to all women, not just infertile women and that we need larger studies to better understand the interaction of these markers.
The women all had to be in the first three months of attempting pregnancy, and without known infertility issues or factors. The women provided blood and urine at the start of the study and then they completed detailed daily diaries of their cycles until pregnancy if possible.
By 6 months, 64% of the women were pregnant. About 80% of women completed at least 1 month of daily diaries. The following table shows the results of the blood and urine.
Steiner, Anne Z. MD, MPH; Herring, Amy H. ScD; Kesner, James S. PhD; Meadows, Juliana W. PhD; Stanczyk, Frank Z. PhD; Hoberman, Steven MS; Baird, Donna D. PhD, MPH; Obstetrics & Gynecology: April 2011 – Volume 117 – Issue 4 – pp 798-804.doi: 10.1097/AOG.0b013e3182116bc8