A prospective study demonstrates that frozen vitrified donor eggs yield the same outcome as fresh donor eggs in this nice prospective study. Egg freezing has been long in the development because the egg (oocyte) is particularly sensitive to the freezing-thawing process.
Take Home Message:
- Vitrified Donor Eggs provided the same outcomes as fresh donor eggs.
- Egg survival was about 89%.
The microtubules inside the egg cell membrane are responsible for the events following fertilization in the completion of meiosis (reduction of chromosomes from 2 copies to 1 copy), second polar body formation (loss of the second set of chromosomes in preparation for fertilization with the male set of chromosomes), migration of pronuclei (the chromosomes from the male and female) and formation of the first mitotic spindle (microtubles that accomplishes this process).
The vitrification technique is also advancing such that smaller volumes of cryoprotectant are required and faster freezing and thawing prevents damage to the egg. This study used a Cryolock devise versus the Cryotop device. The technical details are not so important for this forum but the results are similar.
[ilink url=”http://bit.ly/fzbiVH”]Abstract Link[/ilink]