Researchers found that day 3 embryos biopsied for PGD implanted at the same rate as embryos from non-PGD cycles.
Compared to routine IVF, their blastocyst survival rate after thawing = 87% versus 88% respectively. The implantation and clinical pregnancy rates were 35% versus 29% and 34% versus 36% respectively). The overall ongoing pregnancy rate for all frozen cycles (PGD and IVF/ICSI) was 34%, which compares favorably with the UK national average for frozen cycles (currently 18% live birth rate per thaw).
The authors used this data to encourage eSET (elective single embryo transfer) since the patients would likely have another chance or two for pregnancy is eSET failed on the first attempt.
In my opinion, this is great news for patients who require PGD – the biopsied embryos should have a good chance for creating pregnancy, which was not always accepted as likely. It also gets us closer to eSET for more patients but it does not fully address all patient concerns.