The study showed that the size of the embryo cohort does not affect the rate of normal embryos identified by PGD. The authors used array CGH to evaluate embryos on day 3 and day 5. The study was retrospective using data from a PGD reference lab. They studied 7753 embryos from 990 patients. Embryo Cohort Findings … Read More »
A study published on-line by the journal Obstetrics & Gynecology called “Effect of Hysterectomy With Ovarian Preservation on Ovarian Function” shows that menopause occurs about 2 years earlier in women with hysterectomy compared to women who did not have a hysterectomy. The study is important to infertility patients because one of the main theories regarding … Read More »
I have come to believe that one of the key factors that differentiates IVF outcomes is individualization and management of ovarian stimulation.
Take Home Message on Embryo Quality and Frozen Transfer Cycles: Embryo quality (measured as morphology or shape) remains an important factor for selecting which embryo to transfer. Some clinics do not keep embryo quality information on their frozen embryos. Thus, they randomly transfer embryos in the frozen cycle and their success rates are not optimized … Read More »
Adamson and Pasta propose a new scoring system for endometriosis. They propose an Endometriosis Fertility Index (EFI). The EFI is a combination of surgical factors and historical factors.
How do AMH levels vary throughout a woman’s life? A new study from Denmark provides data from healthy women throughout life. The healthy women data is a great reference source. Turner Syndrome (TS) women demonstrate hormone levels consistent with their ovarian function. [divider] Hagen CP et al. Serum Levels of AMH as a Marker of … Read More »
The authors point out that available evidence suggests that obesity, cigarette smoking, and consumption of alcoholic beverages are associated with diminished female fertility as measured by a longer time-to-pregnancy (TTP) among couples trying to become pregnant or undergoing assisted reproductive technologies. They also note that while there are many studies associating stress with decreased fertility, … Read More »
One of our patients benefited from the use of PGD with array-CGH for recurrent pregnancy loss. We have been very pleased with the technology which now allows us to determine the number of copies for each of the 24 possible chromosomes. Please read the media posting. Recurrent Pregnancy Loss is frequently caused by a genetically … Read More »
The combination of COH (controlled ovarian hyperstimulation) and IUI has been a mainstay of infertility treatment for about 20-25 years. The idea is that if we cause multiple follicles to ovulate and place more sperm in the reproductive tract than would normally swim in on their own then we increase the efficiency of the cycle … Read More »
Genetic technologies invade every aspect of medicine. Here we find another example of a technology that could significantly assist us in identifying the embryo that will make a baby. The authors suggest measuring telomere length may be a measure of embryo health. If so, then this test may be a very valuable tool to access … Read More »