Researchers found that day 3 embryos biopsied for PGD implanted at the same rate as embryos from non-PGD cycles. Compared to routine IVF, their blastocyst survival rate after thawing = 87% versus 88% respectively. The implantation and clinical pregnancy rates were 35% versus 29% and 34% versus 36% respectively). The overall ongoing pregnancy rate for … Read More »
Japanese researchers explored a national database to determine whether thawed single-blast embryo transfer in natural cycles would reduce the risk of an ectopic pregnancy.
A prospective study demonstrates that frozen vitrified donor eggs yield the same outcome as fresh donor eggs in this nice prospective study. Egg freezing has been long in the development because the egg (oocyte) is particularly sensitive to the freezing-thawing process.
Take Home Message on Embryo Quality and Frozen Transfer Cycles: Embryo quality (measured as morphology or shape) remains an important factor for selecting which embryo to transfer. Some clinics do not keep embryo quality information on their frozen embryos. Thus, they randomly transfer embryos in the frozen cycle and their success rates are not optimized … Read More »
[box type=”info” style=”rounded” border=”full”]The authors determined that women with decreased ovarian reserve have an increased risk of forming embryos with trisomy (an embryo with an extra chromosome; Downs syndrome is an extra chromosome 21). The findings were independent of the woman’s age.[/box] The study used the following markers for decreased ovarian reserve: a history of … Read More »
Adamson and Pasta propose a new scoring system for endometriosis. They propose an Endometriosis Fertility Index (EFI). The EFI is a combination of surgical factors and historical factors.
Deep phenotyping to predict live birth outcomes in IVF – the authors suggest that their mathematical model is 100x more accurate than using age to predict IVF outcomes. The authors took data from previous IVF cycles at Stanford and developed a model using complicated statistical tests. They tested the model on IVF cycles from a … Read More »
One of our patients benefited from the use of PGD with array-CGH for recurrent pregnancy loss. We have been very pleased with the technology which now allows us to determine the number of copies for each of the 24 possible chromosomes. Please read the media posting. Recurrent Pregnancy Loss is frequently caused by a genetically … Read More »
The combination of COH (controlled ovarian hyperstimulation) and IUI has been a mainstay of infertility treatment for about 20-25 years. The idea is that if we cause multiple follicles to ovulate and place more sperm in the reproductive tract than would normally swim in on their own then we increase the efficiency of the cycle … Read More »
Australia’s First IVF Baby Turns 30: she wants IVF to be taught as normal process in health education. She says that IVF-lings want to let everyone else know that they are normal people. Click her for the full story. This is a nice story from the perspective of an IVF conceived woman.